Single Use Bioreactor Market Overview
The single use bioreactor market is
anticipated to experience substantial growth from 2025 to 2035, fuelled by growing
demand for quality products has encouraged biologic manufacturers to adopt
single-use bioreactors. With an estimated valuation of approximately USD 4.1
billion in 2025, the market is expected to reach USD 15.1 billion by 2035,
registering a robust compound annual growth rate (CAGR) of 12.6% over the
decade.
Single-use bioreactors are advanced, disposable bioreactors employed mostly in the production of biopharmaceuticals for culturing cells and manufacturing biologics in the form of monoclonal antibodies, vaccines, and gene therapy. In contrast to stainless-steel bioreactors, SUBs employ sterilized plastic bags in a rigid frame that reduces the cleaning and sterilization process to a bare minimum, lowering turnaround time and the cost of operation considerably.
These systems are conducive to
flexible production and are best suited for multi-product and small-batch
manufacturing, particularly in early-stage development, clinical trials, and
research. SUBs have multiple configurations—stirred-tank, wave-induced, and
bubble-column—each designed for specific cell cultures: mammalian, bacterial,
and yeast. These systems provide benefits such as minimized risk of
contamination, less capital investment, and ease of expansion that have made
their use very common in the case of contract manufacturing organizations
(CMOs), biotechnology companies, and the drug industry.
The single-use bioreactor market has
experienced significant expansion in recent times due to the increasing need
for biologics and the move towards modular and adaptive bioproduction plants.
North America and Europe have the highest adoption rates due to established
biotech industries, but the Asia-Pacific region has the potential to grow
strongly. Despite this expansion, areas of material compatibility, waste
management strategies, and capacity in larger-scale production still require to
be tackled. In summary, single-use bioreactors are a revolutionary leap in
terms of bioprocessing because they facilitate accelerated timelines in
developing biologics, cost savings, and manufacturing process agility as a
result.
Single Use Bioreactor Market Drivers and Opportunities
Rising Demand for Biologics and
Personalized Medicine is anticipated to lift the Single Use Bioreactor Market
during the forecast period
​ The upsurge in the need for
biologics—like monoclonal antibodies, recombinant proteins, and gene therapies—is
a key impetus for the single-use bioreactor (SUB) market. Such biologics need
highly controlled and contamination-free conditions to enable production, which
SUBs provide in the form of pre-sterilized and disposable elements. With the
focus of the drug companies leaning towards personalized medicine that involves
small-batch and versatile production, SUBs are even more beneficial given their
adaptability and fast turnaround. The minimized downtime and setup involved in
SUBs enable quicker production cycles to produce desired results sooner. They
are perfect for addressing increasing and diverse demands in biologics
production.
Cost and Time Efficiency in
Bioprocessing drives global Single Use Bioreactor Market
SUBs save a considerable amount of
capital investment in terms of infrastructure, cleaning, sterilization, and
validation in contrast to conventional stainless-steel systems. They are most
appealing to emerging biotechs and contract manufacturing organizations (CMOs)
due to this affordability. They also lower the risks of cross-contamination and
simplify the workflow by ridding the system of the need for elaborate cleaning
procedures between lots. Their flexibilities and speed are major selling points
in today's highly competitive and time-sensitive environment for developing
pharmaceuticals.
Opportunity for the Single Use
Bioreactor Market
Expansion in Emerging Markets is significant
opportunities in the global Single Use Bioreactor Market
The emerging economies of Brazil,
India, and China represent a significant opportunity for the adoption of SUBs.
These economies are investing in life sciences infrastructure and promoting
local drug production. SUBs provide a cost-efficient and scalable alternative
to firms in these economies to start or expand biomanufacturing capacity in a
matter of months without the capital expense of conventional systems. Their
portability, quick deployment, and low operation requirement make them an apt
fit for economies establishing new biotech capacity.
Single
Use Bioreactor Market Scope
Report
Attributes |
Description |
Market Size in 2025 |
USD 4.1 Billion |
Market Forecast in 2035 |
USD 15.1 Billion |
CAGR % 2025-2035 |
12.6% |
Base Year |
2024 |
Historic Data |
2020-2024 |
Forecast Period |
2025-2035 |
Report USP Â |
Production, Consumption, company share, company
heatmap, company production Capacity, growth factors and more |
Segments Covered |
|
Regional Scope |
|
Country Scope |
|
Single
Use Bioreactor Market Report Segmentation Analysis
The global Single Use Bioreactor
Market industry analysis is segmented into by Product, by Type, by Usage Type
by end-user and by region.
Single-use
Bioreactor Systems hold major share In the Single Use Bioreactor Market
Single-use
bioreactor systems represent the bulk of the total single-use bioreactor market
because of their central role in facilitating bioproduction processes. They
comprise a standard disposable bag, sensors, mixers, and control modules and
have the ability to enable aseptic and efficient cell culture without the need
for cleaning or sterilization. Their use is fueled by the increasing need for
biologics and the biopharmaceutical industry's turn to more flexible and
cost-saving manufacturing processes. These systems are very popular for both
commercial and clinical manufacture because of their lower risk of
cross-contamination, quicker setup times, as well as reduced costs of
operation. In addition, evolution in bioprocess monitoring and automation has made
single-use systems more advanced to enable high productivity without
appreciable decline in product quality. Biotechnology firms and CMOs
particularly enjoy having the capacity to perform multiple processes
concurrently without significant infrastructure expenditures, positioning
single-use systems as a pillar technology in flexible biomanufacturing settings.
Stirred-Tank
SUBs type segment contributing major share in the Single Use Bioreactor Market
Stirred-tank single-use bioreactors (SUBs) are the most prevalent in the market, providing the largest market share due to their versatility, scalability, and compatibility in a broad range of cell cultures. Designed following conventional stainless-steel stirred-tank designs, the bioreactors blend the familiar mixing dynamics and the advantage of easily removable consumables. Stirred-tank SUBs have maximum efficiency in culturing mammalian cells used in the production of therapeutic proteins and monoclonal antibodies. They provide precise control of important parameters including oxygen levels, pH levels, and temperatures to yield reproducible and consistent conditions for the cultures. Stirred-tank SUBs are also scalable to pilot and commercial scales starting in the small laboratory volumes. They are also a top pick in various stages of drug development due to their ease of integration into routine work flows, minimal retraining requirement, and compatibility with a vast range of process analytics and monitoring tools. Stirred-tank SUBs' versatility and consistency in performance make this the preferred method for high-capacity biologic production in both industry and research.
Pilot-Scale
Production Usage Type Dominating in Single Use Bioreactor Market
Pilot-scale
production is a crucial step in biopharmaceutical development that bridges the
gap between experimental work in the laboratory and commercial-scale
production. In this process, single-use bioreactors (SUBs) are a key component
that facilitates process optimization and qualification to a scale sufficient
to predict industrial-scale performance but versatile to enable frequent
adjustments. The prevalence of pilot-scale use in the market for SUBs stems
from the fact that it is ideally suited for the testing of new medicines,
biosimilars, and personalized treatments that need to be fast and flexible.
SUBs on a pilot scale enable the manufacturer to reduce risk and cost by
offering quicker batch turns and easier cleaning. They also facilitate the quick
scale-up that a manufacturer needs to commercialize new treatments as rapidly
as possible in a competitive or high-value market segment such as in oncology
or vaccine manufacturing. They also enjoy preference in contract manufacturing
organizations (CMOs) as well as biotech startups that work within a minimal
infrastructure but need dependable, GMP-grade solutions. Their pilot-scale
performance also enhances the probability of adoption to the commercial
production stage in the biomanufacturing pipeline that validates their
strategic role in the pipeline.
The
following segments are part of an in-depth analysis of the global Single Use
Bioreactor Market:
Market Segments |
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By
Product  |
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By
Type   |
|
By
Usage Type |
|
By
End-user |
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Single Use
Bioreactor Market Share Analysis by Region
North
America is projected to hold the largest share of the global Single Use
Bioreactor Market over the forecast period.
North America will lead the global
single-use bioreactor market because of the established biopharmaceutical
sector there, advanced healthcare infrastructure in the region, and the high
investment in research and development. North America has several major
biopharmaceutical and biotech firms that actively embrace advanced bioprocess
technologies, including single-use systems, to increase efficiency, shorten
production duration, and ensure high-quality products. Government support and
conducive regulatory frameworks also promote innovation and commercialization in
biologics, fostering the need for versatile and scalable manufacturing
technologies such as SUBs. The major presence of Thermo Fisher Scientific,
Danaher Corporation, and GE Healthcare in the U.S. also helps the regional
market grow as a result of ongoing product innovation and strategic
collaboration. Further boosting the region’s SUB market in the aftermath of the
pandemic have also been the rising rate of clinical trials and the region’s
quick reaction to public healthcare needs—like the production of COVID-19
vaccines. Contract manufacturers and small biotechs in North America also favor
single-use technologies due to cost-effectiveness, ease of operation, and
high-operating flexibility.
 Market Competition
Landscape Analysis
The market
is competitive, with several established players and new entrants offering a
range single use bioreactors product. Some of the key players Sartorius AG,
Danaher Corporation, Thermo Fisher Scientific Inc., Merck KGaA, Eppendorf SE,
Repligen Corporation, Lonza Group, ABEC Inc. and Others.
Global Single
Use Bioreactor Market Recent Developments News:
The
global single use bioreactor market is
dominated by a few large companies, such as
·       Â
Sartorius AG
·       Â
Danaher Corporation
·       Â
Thermo Fisher Scientific
Inc.
·       Â
Merck KGaA
·       Â
Eppendorf SE
·       Â
Getinge AB
·       Â
Pall Corporation
·       Â
Repligen Corporation
·       Â
Lonza Group
·       Â
ABEC Inc.
·       Â
Applikon Biotechnology
·       Â
PBS Biotech Inc.
·       Â
Distek Inc.
·       Â
Saint-Gobain
·       Â
OmniBRx Biotechnologies
·       Â
Other Prominent PlayersÂ
1.      Global
Single Use Bioreactor Market Introduction and Market Overview
1.1.  Â
Objectives of the Study
1.2.  Â
Global Single Use Bioreactor Market
Scope and Market Estimation
1.2.1.Global Single
Use Bioreactor Market Overall Market Size (US$ Bn), Market CAGR (%), Market forecast
(2025 - 2035)
1.2.2.Global Single
Use Bioreactor Market Revenue Share (%) and Growth Rate (Y-o-Y) from 2021 - 2035
1.3.  Â
Market Segmentation
1.3.1.Product of
Global Single Use Bioreactor Market
1.3.2.Type of
Global Single Use Bioreactor Market
1.3.3.Usage Type
of Global Single Use Bioreactor Market
1.3.4.End-user
of Global Single Use Bioreactor Market
1.3.5.Region of
Global Single Use Bioreactor Market
2.      Executive Summary
2.1.  Â
Demand Side Trends
2.2.  Â
Key Market Trends
2.3.  Â
Market Demand (US$ Bn) Analysis 2021 –
2024 and Forecast, 2025 – 2035
2.4.  Â
Demand and Opportunity Assessment
2.5.  Â
Demand Supply Scenario
2.6.  Â
Market Dynamics
2.6.1.Drivers
2.6.2.Limitations
2.6.3.Opportunities
2.6.4.Impact
Analysis of Drivers and Restraints
2.7.  Â
Emerging Trends for Single Use
Bioreactor Market
2.8.  Â
Pricing Analysis
2.9.  Â
Key Products/Brand Analysis Â
2.10. Porter’s
Five Forces Analysis
2.10.1.  Â
Bargaining Power of Suppliers
2.10.2.  Â
Bargaining Power of Buyers
2.10.3.  Â
Threat of Substitutes
2.10.4.  Â
Threat of New Entrants
2.10.5.  Â
Competitive Rivalry
2.11. PEST
Analysis
2.11.1.  Â
Political Factors
2.11.2.  Â
Economic Factors
2.11.3.  Â
Social Factors
2.11.4.  Â
Product Factors
2.12. Key
Regulation
3.      Global Single Use Bioreactor Market Estimates &
Historical Trend Analysis (2021 - 2024)
4.     Â
Global
Single Use Bioreactor Market Estimates & Forecast Trend Analysis, by Product
4.1.  Â
Global Single Use Bioreactor Market
Revenue (US$ Bn) Estimates and Forecasts, by Product, 2021 - 2035
4.1.1.Single-use
Bioreactor Systems
4.1.2.Single-use
Media Bags
4.1.3.Single-use
Filtration Assemblies
4.1.4.Others
5.     Â
Global
Single Use Bioreactor Market Estimates & Forecast Trend Analysis, by Type
5.1.  Â
Global Single Use Bioreactor Market
Revenue (US$ Bn) Estimates and Forecasts, by Type, 2021 - 2035
5.1.1.1.            Â
Stirred-Tank SUBs
5.1.1.2.            Â
Wave-Induced SUBs
5.1.1.3.            Â
Bubble-Column SUBs
5.1.1.4.            Â
Others
6.     Â
Global
Single Use Bioreactor Market Estimates & Forecast Trend Analysis, by Usage Type
6.1.  Â
Global Single Use Bioreactor Market
Revenue (US$ Bn) Estimates and Forecasts, by Usage Type, 2021 - 2035
6.1.1.Lab-Scale
Production
6.1.2.Pilot-Scale
Production
6.1.3.Large-Scale
Production
7.     Â
Global
Single Use Bioreactor Market Estimates & Forecast Trend Analysis, by End-user
7.1.  Â
Global Single Use Bioreactor Market
Revenue (US$ Bn) Estimates and Forecasts, by End-user, 2021 - 2035
7.1.1.Pharmaceutical
& Biopharmaceutical Companies
7.1.2.CROs and
CDMOs
7.1.3.Academic
& Research Institutes
8.      Global Single Use Bioreactor Market Estimates &
Forecast Trend Analysis,
by region
1.1.  Â
Global Single Use Bioreactor Market
Revenue (US$ Bn) Estimates and Forecasts, by region, 2021 - 2035
1.1.1.North
America
1.1.2.Eastern
Europe
1.1.3.Western
Europe
1.1.4.Asia
Pacific
1.1.5.Middle
East & Africa
1.1.6.Latin
America
9.      North
America Single Use
Bioreactor Market: Estimates &
Forecast Trend Analysis
9.1.   North
America Single Use Bioreactor Market Assessments & Key Findings
9.1.1.North
America Single Use Bioreactor Market Introduction
9.1.2.North
America Single Use Bioreactor Market Size Estimates and Forecast (US$ Billion)
(2021 - 2035)
9.1.2.1. Â
By Product
9.1.2.2. Â
By Type
9.1.2.3. Â
By Usage Type
9.1.2.4. Â
By End-user
9.1.2.5. Â
By Country
9.1.2.5.1.   Â
The U.S.
9.1.2.5.2.   Â
Canada
9.1.2.5.3.   Â
Mexico
10.  Western
Europe Single Use
Bioreactor Market: Estimates &
Forecast Trend Analysis
10.1. Western
Europe Single Use Bioreactor Market Assessments & Key Findings
10.1.1. Â
Western Europe Single Use Bioreactor
Market Introduction
10.1.2. Â
Western Europe Single Use Bioreactor
Market Size Estimates and Forecast (US$ Billion) (2021 - 2035)
10.1.2.1.  Â
By Product
10.1.2.2.  Â
By Type
10.1.2.3.  Â
By Usage Type
10.1.2.4.  Â
By End-user
10.1.2.5.  Â
By Country
10.1.2.5.1. Germany
10.1.2.5.2. Italy
10.1.2.5.3. U.K.
10.1.2.5.4. France
10.1.2.5.5. Spain
10.1.2.5.6. Benelux
10.1.2.5.7. Nordics
10.1.2.5.8. Rest of W. Europe
11.  Eastern
Europe Single Use
Bioreactor Market: Estimates &
Forecast Trend Analysis
11.1. Eastern
Europe Single Use Bioreactor Market Assessments & Key Findings
11.1.1. Â
Eastern Europe Single Use Bioreactor
Market Introduction
11.1.2. Â
Eastern Europe Single Use Bioreactor
Market Size Estimates and Forecast (US$ Billion) (2021 - 2035)
11.1.2.1.  Â
By Product
11.1.2.2.  Â
By Type
11.1.2.3.  Â
By Usage Type
11.1.2.4.  Â
By End-user
11.1.2.5.  Â
By Country
11.1.2.5.1. Russia
11.1.2.5.2. Hungary
11.1.2.5.3. Poland
11.1.2.5.4. Balkan & Baltics
11.1.2.5.5. Rest of E. Europe
12.  Asia
Pacific Single Use
Bioreactor Market: Estimates &
Forecast Trend Analysis
12.1. Asia
Pacific Market Assessments & Key Findings
12.1.1.  Â
Asia Pacific Single Use Bioreactor
Market Introduction
12.1.2.  Â
Asia Pacific Single Use Bioreactor
Market Size Estimates and Forecast (US$ Billion) (2021 - 2035)
12.1.2.1.  Â
By Product
12.1.2.2.  Â
By Type
12.1.2.3.  Â
By Usage Type
12.1.2.4.  Â
By End-user
12.1.2.5.  Â
By Country
12.1.2.5.1.
China
12.1.2.5.2.
Japan
12.1.2.5.3.
India
12.1.2.5.4.
Australia & New Zealand
12.1.2.5.5.
South Korea
12.1.2.5.6.
ASEAN
12.1.2.5.7. Rest
of Asia Pacific
13.  Middle
East & Africa Single
Use Bioreactor Market: Estimates &
Forecast Trend Analysis
13.1. Middle
East & Africa Market Assessments & Key Findings
13.1.1. Â
Middle East
& Africa Single Use Bioreactor Market Introduction
13.1.2. Â
Middle East
& Africa Single Use Bioreactor Market Size Estimates
and Forecast (US$ Billion) (2021 - 2035)
13.1.2.1.  Â
By Product
13.1.2.2.  Â
By Type
13.1.2.3.  Â
By Usage Type
13.1.2.4.  Â
By End-user
13.1.2.5.  Â
By Country
13.1.2.5.1.
UAE
13.1.2.5.2.
Saudi Arabia
13.1.2.5.3.
Turkey
13.1.2.5.4.
South Africa
13.1.2.5.5. Rest of MEA
14.  Latin
America Single
Use Bioreactor Market: Estimates &
Forecast Trend Analysis
14.1. Latin
America Market Assessments & Key Findings
14.1.1. Â
Latin America Single Use Bioreactor
Market Introduction
14.1.2. Â
Latin America Single Use Bioreactor
Market Size Estimates and Forecast (US$ Billion) (2021 - 2035)
14.1.2.1.  Â
By Product
14.1.2.2.  Â
By Type
14.1.2.3.  Â
By Usage Type
14.1.2.4.  Â
By End-user
14.1.2.5.  Â
By Country
14.1.2.5.1.
Brazil
14.1.2.5.2.
Argentina
14.1.2.5.3.
Colombia
14.1.2.5.4. Rest of LATAM
15.  Country
Wise Market: Introduction
16. Â
Competition Landscape
16.1. Global
Single Use Bioreactor Market Product Mapping
16.2. Global
Single Use Bioreactor Market Concentration Analysis, by Leading Players / Innovators
/ Emerging Players / New Entrants
16.3. Global
Single Use Bioreactor Market Tier Structure Analysis
16.4. Global
Single Use Bioreactor Market Concentration & Company Market Shares (%)
Analysis, 2023
17. Â
Company Profiles
17.1.     Sartorius AG
17.1.1.  Â
Company Overview & Key Stats
17.1.2.  Â
Financial Performance & KPIs
17.1.3.  Â
Product Portfolio
17.1.4.  Â
SWOT Analysis
17.1.5.  Â
Business Strategy & Recent
Developments
   *
Similar details would be provided for all the players mentioned belowÂ
17.2.    Â
Danaher Corporation
17.3.    Â
Thermo Fisher
Scientific Inc.
17.4.    Â
Merck KGaA
17.5.    Â
Eppendorf SE
17.6.    Â
GE Healthcare
17.7.    Â
Pall Corporation
17.8.    Â
Repligen Corporation
17.9.    Â
Lonza Group
17.10. Â
ABEC Inc.
17.11. Â
Applikon Biotechnology
17.12. Â
PBS Biotech Inc.
17.13. Â
Distek Inc.
17.14. Â
Saint-Gobain
17.15. Â
OmniBRx
Biotechnologies
17.16. Â
Other Prominent
Players
18.  Research Methodology
18.1. External
Transportations / Databases
18.2. Internal
Proprietary Database
18.3. Primary
Research
18.4. Secondary
Research
18.5. Assumptions
18.6. Limitations
18.7. Report
FAQs
19.  Research Findings & Conclusion
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Single Use Bioreactor Market was valued at USD 4.1 Billion in 2025.
Single Use Bioreactor Market size will increase at approximate CAGR of 12.6% during the forecasted period.
Major companies operating within the market Sartorius AG, Danaher Corporation, Thermo Fisher Scientific Inc., Merck KGaA, Eppendorf SE, Repligen Corporation, Lonza Group, ABEC Inc. and Others.
North America dominates the Single Use Bioreactor Market over the forecasting period.
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