Adagrasib Market Analysis by Indication (Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer, Other Solid Tumors), By Treatment Type (Monotherapy, Combination Therapy), By Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies) and by Region: Global Forecast, 2024 - 2034
- PUBLISHED ON
- 2024-05-03
- NO OF PAGES
- 191
- CATEGORY
- Healthcare & Life Sciences
Market Overview
The Adagrasib market is predicted to develop at a compound annual growth rate (CAGR) of XX% from 2024 to 2034, when it is projected to reach USD XX Million, based on an average growth pattern. The market is estimated to reach a value of USD XX Million in 2024.
SOURCE: We Market Research
Adagrasib is a
medication used in targeted therapy that blocks KRAS G12C, a particular kind of
mutant protein. This mutation is frequently detected in some cancer types,
including colorectal and non-small cell lung cancer (NSCLC). Adagrasib
functions by preventing the mutant KRAS protein from acting, which is essential
in fostering the development of cancer. Adagrasib works to slow down or stop
the proliferation of cancer cells that carry the KRAS G12C mutation by blocking
this protein. It is being investigated in clinical studies for its efficacy and
safety in treating various kinds of tumors, and it represents a potential strategy
in targeted cancer therapy.
Mirati Therapeutics produced the oral small-molecule KRAS inhibitor Adagrasib (MRTX849). KRAS mutations make up about 85% of all RAS family mutations and are extremely prevalent in cancer. However, because of their strong affinity for GTP and GDP and because they lack a well-defined binding site, the creation of KRAS inhibitors has proven difficult. Adagrasib suppresses KRAS-dependent signaling by targeting the cysteine 12 residue of KRASG12C, one of the most prevalent KRAS mutations. Adagrasib demonstrated anti-tumor effects in a phase I/IB clinical research including patients with advanced solid tumors with mutations in KRASG12C (NCT03785249). Phase II of the same trial demonstrated that adagrasib was effective without additional safety signals in patients with non-small-cell lung cancer (NSCLC) with a mutation in the KRASG12C gene.Â
Market Scope
|
Report Attributes |
Description |
|
Market Size in 2024 |
USD XX Million |
|
Market Forecast in 2034 |
USD XX Million |
|
CAGR % 2024-2034 |
XX% |
|
Base Year |
2023 |
|
Historic Data |
2016-2022 |
|
Forecast Period |
2024-2034 |
|
Report USP Â |
Production, Consumption, company share, company
heatmap, company production capacity, growth factors and more |
|
Segments Covered |
By Indication, By Treatment Type, By Distribution Channel and By
Region |
|
Regional Scope |
North America, Europe, APAC, South America and
Middle East and Africa |
|
Country Scope |
U.S.; Canada; U.K.; Germany; France; Italy; Spain; Benelux; Nordic
Countries; Russia; China; India; Japan; South Korea; Australia; Indonesia;
Thailand; Mexico; Brazil; Argentina; Saudi Arabia; UAE; Egypt; South Africa;
Nigeria |
Â
Adagrasib Industry: Dynamics & Restrains
We Market Research: Adagrasib Dashboard
Our marketing platform offers a comprehensive dashboard that provides clients with valuable insights into market trends over the years. Included below is a sample image of our dashboard, and specific PDF logins will be furnished to grant access to this insightful tool.
Adagrasib Segmentation
Market- By Indication Analysis
By Indication, the Adagrasib Market is Categories into Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer, Other Solid Tumors. The Non-Small Cell Lung Cancer (NSCLC) segment accounts for the largest share of around 68% in 2024.
Adagrasib is used to treat non-small cell
lung cancer (NSCLC) because of its potency against certain genetic alterations,
such as KRAS G12C, which is frequently present in NSCLC patients. Adagrasib is
a viable treatment option for individuals with NSCLC who have this genetic
alteration because of its focused suppression of this mutation, which lowers
tumor growth.
The
following segments are part of an in-depth analysis of the global Adagrasib
market:
|
Market Segments |
 |
|
By  Treatment
Type |
·       Â
Monotherapy ·       Â
Combination Therapy |
|
By  Distribution
Channel |
·       Â
Hospital Pharmacies ·       Â
Retail Pharmacies ·       Â
Online Pharmacies |
Â
Adagrasib Industry: Regional Analysis
North America Market Forecast
North America dominate the Adagrasib Market with the highest revenue generating market with share of more than 47%. Adagrasib is widely utilized in the treatment of NSCLC patients, owing to the high frequency of KRAS G12C mutations, particularly in the United States and Canada. Adagrasib's use in this arena has been accelerated by the FDA's approval of the medicine for NSCLC patients with KRAS G12C mutations.
Europe Market Statistics
Europe is the
second largest region in Adagrasib market, due the factors driving market
expansion include increased awareness of precision medicine, favorable
government initiatives supporting cancer research, and the presence of
significant pharmaceutical companies creating novel medicines such as
Adagrasib. Furthermore, connections between academic institutions and
pharmaceutical businesses help to strengthen research activities in the region.
Asia Pacific Market Forecasts
Asia Pacific is
expected to be the fastest-growing regional segment of the Adagrasib market
during the forecast period. The Adagrasib market in Asia Pacific region is
fueled by factors such as a huge population base, rising cancer incidence, and
improved healthcare infrastructure. Furthermore, rising healthcare expenditure,
increased investments in the biotechnology and pharmaceutical sectors, and
expanding knowledge about customized medicine all contribute to market growth
in countries such as China, India, and Japan.
Key Market Players       Â
The Adagrasib Market is dominated by a few large companies, such as
·       Â
Mirati Therapeutics
·        Amgen
·         Other
1.    Â
Global
Adagrasib Market Introduction and Market Overview
1.1.   Objectives of the Study
1.2.   Global Adagrasib Market Scope
and Market Estimation
1.2.1. Global Adagrasib Overall Market
Size, Revenue (US$ Mn), Market CAGR (%), Market forecast (2023 - 2034)
1.2.2. Global Adagrasib Market Revenue
Share (%) and Growth Rate (Y-o-Y) from 2019 - 2034
1.3.   Market Segmentation
1.3.1. Component of Global Adagrasib
Market
1.3.2. Technology of Global Adagrasib
Market
1.3.3. Distribution Channel of Global Adagrasib
Market
1.3.4. Region of Global Adagrasib
Market
2.    Â
Executive Summary
2.1.   Global Adagrasib Market Industry Trends under COVID-19 Outbreak
2.1.1. Global COVID-19 Status Overview
2.1.2. Influence of COVID-19 Outbreak
on Global Adagrasib Market
Industry Development
2.2.   Market Dynamics
2.2.1. Drivers
2.2.2. Limitations
2.2.3. Opportunities
2.2.4. Impact Analysis of Drivers and
Restraints
2.3.   Pricing Trends Analysis &
Average Selling Prices (ASPs)
2.4.   Key Mergers & Acquisitions,
Expansions, JVs, Funding / VCs, etc.
2.5.   Porter’s Five Forces Analysis
2.5.1. Bargaining Power of Suppliers
2.5.2. Bargaining Power of Buyers
2.5.3. Threat of Substitutes
2.5.4. Threat of New Entrants
2.5.5. Competitive Rivalry
2.6.   Value Chain / Ecosystem Analysis
2.7.   Russia-Ukraine War Impacts
Analysis
2.8.   Economic Downturn Analysis
2.9.     Market Investment Opportunity
Analysis (Top Investment Pockets), By Segments & By Region
3.    Â
Global Adagrasib Market Estimates & Historical Trend Analysis (2019 -
2023)
4.    Â
Global Adagrasib Market Estimates & Forecast Trend Analysis, by
INDICATION
4.1.   Global Adagrasib Market Revenue
(US$ Mn) Estimates and Forecasts, by INDICATION, 2019 to 2034
4.1.1. Non-Small Cell Lung Cancer
(NSCLC)
4.1.2. Colorectal Cancer
4.1.3. Other Solid Tumors
5.    Â
Global Adagrasib Market Estimates & Forecast Trend Analysis, by
Treatment Type
5.1.   Global Adagrasib Market Revenue
(US$ Mn) Estimates and Forecasts, by Treatment Type, 2019 to 2034
5.1.1. Monotherapy
5.1.2. Combination Therapy
6.    Â
Global Adagrasib Market Estimates & Forecast Trend Analysis, by
Distribution Channel
6.1.   Global Adagrasib Market Revenue
(US$ Mn) Estimates and Forecasts, by Distribution
Channel, 2019 to 2034
6.1.1. Hospital Pharmacies
6.1.2. Retail Pharmacies
6.1.3. Online Pharmacies
7.    Â
Global Adagrasib Market Estimates & Forecast Trend Analysis,
by Region
7.1.   Global Adagrasib Market Revenue
(US$ Mn) Estimates and Forecasts, by Region, 2019 to 2034
7.1.1. North America
7.1.2. Europe
7.1.3. Asia Pacific
7.1.4. Middle East & Africa
7.1.5. South America
8.    Â
North
America Adagrasib Market: Estimates & Forecast Trend Analysis
8.1.  Â
North
America Adagrasib Market Assessments & Key Findings
8.1.1. North America Adagrasib Market
Introduction
8.1.2. North America Adagrasib Market
Size Estimates and Forecast (US$ Million) (2019 – 2034)
8.1.2.1.  By INDICATION
8.1.2.2.  By Treatment Type
8.1.2.3.  By Distribution
Channel
8.1.2.4.  By Country
8.1.2.4.1.    The U.S.
8.1.2.4.2.    Canada
8.1.2.4.3.    Mexico
9.    Â
Europe
Adagrasib Market: Estimates & Forecast Trend Analysis
9.1.   Europe Adagrasib Market
Assessments & Key Findings
9.1.1. Europe Adagrasib Market
Introduction
9.1.2. Europe Adagrasib Market Size
Estimates and Forecast (US$ Million) (2019 – 2034)
9.1.2.1.  By INDICATION
9.1.2.2.  By Treatment Type
9.1.2.3.  By Distribution
Channel
9.1.2.4.      Â
By
Country
9.1.2.4.1.    Germany
9.1.2.4.2.    U.K.
9.1.2.4.3.    France
9.1.2.4.4.    Italy
9.1.2.4.5.    Spain
9.1.2.4.6.    Russia
9.1.2.4.7.    Rest of Europe
10. Asia Pacific Adagrasib
Market: Estimates & Forecast Trend
Analysis
10.1. Asia Pacific Market Assessments
& Key Findings
10.1.1.  Asia Pacific Adagrasib Market
Introduction
10.1.2.  Asia Pacific Adagrasib Market
Size Estimates and Forecast (US$ Million) (2019 – 2034)
10.1.2.1.   By INDICATION
10.1.2.2.   By Treatment Type
10.1.2.3.   By Distribution
Channel
10.1.2.4.   By Country
10.1.2.4.1. China
10.1.2.4.2. Japan
10.1.2.4.3. India
10.1.2.4.4. Australia
10.1.2.4.5. South Korea
10.1.2.4.6. ASEAN
10.1.2.4.7. Rest of Asia Pacific
11. Middle East & Africa Adagrasib
Market: Estimates & Forecast Trend
Analysis
11.1. Middle East & Africa Market
Assessments & Key Findings
11.1.1.  Middle
East & Africa Adagrasib
Market Introduction
11.1.2.  Middle
East & Africa Adagrasib
Market Size Estimates and Forecast (US$ Million) (2019 – 2034)
11.1.2.1.   By INDICATION
11.1.2.2.   By Treatment Type
11.1.2.3.   By Distribution
Channel
11.1.2.4.   By Country
11.1.2.4.1. U.A.E.
11.1.2.4.2. Saudi Arabia
11.1.2.4.3. Egypt
11.1.2.4.4. South Africa
11.1.2.4.5. Rest of Middle East & Africa
12. South America
Adagrasib Market: Estimates &
Forecast Trend Analysis
12.1. South America Market Assessments
& Key Findings
12.1.1.  South America Adagrasib Market
Introduction
12.1.2.  South America Adagrasib Market
Size Estimates and Forecast (US$ Million) (2019 – 2034)
12.1.2.1.   By INDICATION
12.1.2.2.   By Treatment Type
12.1.2.3.   By Distribution
Channel
12.1.2.4.   By Country
12.1.2.4.1. Brazil
12.1.2.4.2. Argentina
12.1.2.4.3. Colombia
12.1.2.4.4. Rest of South America
13. Competition Landscape
13.1. Global Adagrasib Market
Competition Matrix & Benchmarking, by Leading Players / Innovators /
Emerging Players / New Entrants
13.2. Global Adagrasib Market
Competition White Space Analysis, By Distribution Channel
13.3. Global Adagrasib Market
Competition Heat Map Analysis, By Distribution Channel
13.4. Global Adagrasib Market
Concentration & Company Market Shares (%) Analysis, 2022
14. Company Profiles
14.1.                   Â
Mirati Therapeutics
14.1.1.  Company Overview & Key Stats
14.1.2.  Financial Performance & KPIs
14.1.3.  Product Portfolio
14.1.4.  Business Strategy & Recent
Developments
* Similar details would be provided
for all the players mentioned belowÂ
14.2.     Amgen
14.3.     Others
15. Research
Methodology
15.1. External Transportations /
Databases
15.2. Internal Proprietary Database
15.3. Primary Research
15.4. Secondary Research
15.5. Assumptions
15.6. Limitations
15.7. Report FAQs
16. Research Findings & Conclusion
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Frequently Asked Questions
What is the market size of Adagrasib Market in 2024?
Adagrasib Market was valued at USD XX Million in 2024.
What is the growth rate for the Adagrasib Market?
Adagrasib Market size will increase at approximate CAGR of XX% during the forecasted period.
Which are the top companies operating within the market?
Major companies operating within the Adagrasib Market Are Mirati Therapeutics, Amgen and Other.
Which region dominates the Adagrasib Market?
North America dominates the market with an active share of 47%.
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